4YOC
Crystal Structure of human DNMT1 and USP7/HAUSP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (cytosine-5)-methyltransferase 1 | polymer | 1004 | 113916.8 | 1 | UniProt (P26358) Pfam (PF02008) Pfam (PF01426) Pfam (PF00145) | Homo sapiens (Human) | Dnmt1,CXXC-type zinc finger protein 9,DNA methyltransferase HsaI,M.HsaI,MCMT |
| 2 | B (C) | Ubiquitin carboxyl-terminal hydrolase 7 | polymer | 548 | 64106.0 | 1 | UniProt (Q93009) Pfam (PF12436) Pfam (PF14533) | Homo sapiens (Human) | Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7 |
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F (A, C) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 600 - 1600 (UniProt: P26358)
C: 560 - 1102 (UniProt: Q93009)
| PDB | External Database | Details |
|---|---|---|
| Ser 597 | - | expression tag |
| Glu 598 | - | expression tag |
| Phe 599 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 555 | - | expression tag |
| Pro 556 | - | expression tag |
| Leu 557 | - | expression tag |
| Gly 558 | - | expression tag |
| Ser 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 178022.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 178153.7 |
