4YO8

Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with (((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)(hexyl)amino)methanol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Aminodeoxyfutalosine nucleosidase	polymer	245	26886.9	2	UniProt (Q9ZMY2)	Helicobacter pylori	Aminofutalosine nucleosidase,5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase,MTAN,6-amino-6-deoxyfutalosine N-ribosylhydrolase
2	C, E (A, B)	{[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl](hexyl)amino}methanol	non-polymer		277.4	2	Chemie (4EZ)
3	D (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	F, G (A, B)	water	water		18.0	100	Chemie (HOH)

Sequence modifications

A, B: 3 - 231 (UniProt: Q9ZMY2)

PDB	External Database	Details
Met -13	-	initiating methionine
Gly -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Gly 1	-	expression tag
Val 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53773.8
Non-Polymers*	Number of molecules	3
	Total formula weight	620.1
All*	Total formula weight	54393.9

*Water molecules are not included.