4YN4
Structure of human DNA polymerase beta complexed with N7BG in the template opposite to incoming non-hydrolyzable dTTP WITH MANGANESE IN THE ACTIVE SITE
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (Human) | |
2 | B (T) | DNA 16-mer (template) | polymer | 16 | 4953.3 | 1 | Homo sapiens | ||
3 | C (P) | DNA 10-mer (up-primer) | polymer | 10 | 3085.0 | 1 | Homo sapiens | ||
4 | D (D) | DNA 5-mer (dn-primer) | polymer | 5 | 1536.0 | 1 | Homo sapiens | ||
5 | E, F (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
6 | G, H (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
7 | I (A) | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine | non-polymer | 481.2 | 1 | Chemie (1FZ) | |||
8 | J, K, L, M (A, T, P, D) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 47816.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 637.0 | |
All* | Total formula weight | 48453.0 |