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4YN4

Structure of human DNA polymerase beta complexed with N7BG in the template opposite to incoming non-hydrolyzable dTTP WITH MANGANESE IN THE ACTIVE SITE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
DNA 16-mer (template)polymer164953.31Homo sapiens
3C
(P)
DNA 10-mer (up-primer)polymer103085.01Homo sapiens
4D
(D)
DNA 5-mer (dn-primer)polymer51536.01Homo sapiens
5E, F
(A)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidinenon-polymer481.21Chemie (1FZ)
8J, K, L, M
(A, T, P, D)
waterwater18.0119Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47816.0
Non-Polymers*Number of molecules5
Total formula weight637.0
All*Total formula weight48453.0
*Water molecules are not included.

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PDB entries from 2024-11-13

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