4YML
Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with (3S,4R)-methylthio-DADMe-Immucillin-A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | polymer | 245 | 26058.7 | 1 | UniProt (P0AF12) Pfam (PF01048) In PDB | Escherichia coli | MTAN,5'-methylthioadenosine nucleosidase,MTA nucleosidase,P46,S-adenosylhomocysteine nucleosidase,SRH nucleosidase |
2 | A | (3S,4R)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(methylsulfanyl)methyl]pyrrolidin-3-ol | non-polymer | 293.4 | 1 | Chemie (4F0) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 1 - 232 (UniProt: P0AF12)
PDB | External Database | Details |
---|---|---|
Glu 233 | - | expression tag |
Asn 234 | - | expression tag |
Leu 235 | - | expression tag |
Tyr 236 | - | expression tag |
Phe 237 | - | expression tag |
Gln 238 | - | expression tag |
Gly 239 | - | expression tag |
His 240 | - | expression tag |
His 241 | - | expression tag |
His 242 | - | expression tag |
His 243 | - | expression tag |
His 244 | - | expression tag |
His 245 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26058.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 388.4 | |
All* | Total formula weight | 26447.1 |