4YMA
Structure of the ligand-binding domain of GluA2 in complex with the antagonist CNG10109
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Glutamate receptor 2 | polymer | 264 | 29278.7 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
2 | B, A | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
3 | B, A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | B, A | (3R)-3-(3-carboxy-5-hydroxyphenyl)-L-proline | non-polymer | 251.2 | 2 | Chemie (4E5) | |||
5 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
7 | water | water | 18.0 | 698 | Chemie (HOH) |
Sequence modifications
B, A: 3 - 117 (UniProt: P19491)
B, A: 120 - 264 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Ala 2 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | linker |
Thr 119 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58557.5 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1446.2 | |
All* | Total formula weight | 60003.7 |