Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | LYS144 |
| B | ARG148 |
| B | ARG163 |
| B | HOH409 |
| B | HOH410 |
| B | HOH428 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | HOH767 |
| B | HOH770 |
| B | HOH774 |
| B | HOH775 |
| B | LYS60 |
| B | TYR61 |
| B | 4E5304 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | HIS46 |
| B | LYS240 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue 4E5 B 304 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | LEU138 |
| B | SER142 |
| B | THR143 |
| B | GLU193 |
| B | SO4302 |
| B | HOH522 |
| B | HOH532 |
| B | HOH571 |
| B | HOH735 |
| B | HOH763 |
| B | HOH774 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| A | LEU26 |
| B | GLU30 |
| B | HOH433 |
| B | HOH526 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | LYS116 |
| B | HOH588 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 301 |
| Chain | Residue |
| A | PRO105 |
| A | PHE106 |
| A | MET107 |
| A | SER108 |
| A | ASN242 |
| A | HOH611 |
| B | SER217 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 302 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | LYS144 |
| A | ARG148 |
| A | HOH404 |
| A | HOH676 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | LYS82 |
| A | LYS185 |
| A | HOH428 |
| A | HOH432 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | LYS60 |
| A | TYR61 |
| A | 4E5307 |
| A | HOH664 |
| A | HOH695 |
| A | HOH703 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 306 |
| Chain | Residue |
| A | HIS46 |
| A | ALA233 |
| A | LEU236 |
| A | ALA237 |
| A | LYS240 |
| A | HOH687 |
| site_id | AD4 |
| Number of Residues | 14 |
| Details | binding site for residue 4E5 A 307 |
| Chain | Residue |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | LEU138 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| A | SO4305 |
| A | HOH504 |
| A | HOH527 |
| A | HOH571 |
| A | HOH691 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | PRO89 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| B | THR91 | |
| B | ARG96 | |
| B | SER142 | |
| B | THR143 | |
| B | GLU193 | |
| A | PRO89 | |
| A | THR91 | |
| A | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| B | ILE121 | |
| A | ILE121 | |
| Chain | Residue | Details |
| B | SER150 | |
| A | SER150 | |
| Chain | Residue | Details |
| B | SER184 | |
| A | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN3 | |
| A | ASN3 | |
