4YJT
THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000233
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase SYK | polymer | 281 | 32810.6 | 1 | UniProt (P43405) Pfam (PF07714) | Homo sapiens (Human) | Spleen tyrosine kinase,p72-Syk |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | N~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-N~4~-ethyl-5-fluoro-N~4~-(1H-indazol-4-yl)pyrimidine-2,4-diamine | non-polymer | 439.5 | 1 | Chemie (4DQ) | |||
| 4 | D (A) | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32810.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 531.6 | |
| All* | Total formula weight | 33342.2 |
