4YJL

Crystal structure of APC-ARM in complexed with Amer1-A2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Adenomatous polyposis coli protein	polymer	354	39268.2	6	UniProt (P25054) Pfam (PF18797) Pfam (PF00514)	Homo sapiens (Human)	Protein APC,Deleted in polyposis 2.5
2	G, H, I, J, K... (G, H, I, J, K...)	APC membrane recruitment protein 1	polymer	13	1520.6	6	UniProt (Q5JTC6)	Homo sapiens	Amer1,Protein FAM123B,Wilms tumor gene on the X chromosome protein
3	AA, BA, CA, DA, EA... (C, D, A, E, F...)	1,2-ETHANEDIOL	non-polymer		62.1	37	Chemie (EDO)
4	AB, BB, CB, DB, EB... (D, E, F, G, H...)	water	water		18.0	2397	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 407 - 751 (UniProt: P25054)

PDB	External Database	Details
Met 398	-	expression tag
Gly 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
Met 406	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	244732.9
Non-Polymers*	Number of molecules	37
	Total formula weight	2296.5
All*	Total formula weight	247029.5

*Water molecules are not included.