4YIZ
Crystal structure of engineered TgAMA1 lacking the DII loop in complex with an Eimeria tenella RON2D3 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, E) | Apical membrane antigen AMA1 | polymer | 419 | 46064.3 | 3 | UniProt (S8GKS3) Pfam (PF02430) UniProt (by SIFTS) (B6KAM0) | Toxoplasma gondii ME49 | |
| 2 | D, E, F (B, D, F) | Rhoptry neck protein 2, putative | polymer | 40 | 3872.4 | 3 | UniProt (U6KQJ2) UniProt (by SIFTS) (B6KV60) | Eimeria tenella (Coccidian parasite) | |
| 3 | G, K, N (A, C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | H (A) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) | |||
| 5 | I, J, L, M, O (A, C, E) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | P, Q, R, S, T... (A, C, E, B, D...) | water | water | 18.0 | 487 | Chemie (HOH) |
Sequence modifications
A, C, E: 64 - 484 (UniProt: S8GKS3)
B, D, F: 1261 - 1297 (UniProt: U6KQJ2)
| PDB | External Database | Details |
|---|---|---|
| Gly 59 | - | expression tag |
| Ser 60 | - | expression tag |
| Ala 61 | - | expression tag |
| Met 62 | - | expression tag |
| Gly 63 | - | expression tag |
| - | His 340 | deletion |
| - | Thr 341 | deletion |
| - | Tyr 342 | deletion |
| - | Pro 343 | deletion |
| - | Leu 344 | deletion |
| - | Thr 345 | deletion |
| - | Ser 346 | deletion |
| - | Gln 347 | deletion |
| - | Ala 348 | deletion |
| - | Ser 349 | deletion |
| - | Trp 350 | deletion |
| - | Asn 351 | deletion |
| - | Asp 352 | deletion |
| Gly 353 | Trp 353 | linker |
| Ser 354 | Trp 354 | linker |
| Gly 355 | Pro 355 | linker |
| Ser 356 | Leu 356 | linker |
| Gly 357 | His 357 | linker |
| Ser 358 | Gln 358 | linker |
| Gly 359 | Ser 359 | linker |
| Ala 485 | - | expression tag |
| Ala 486 | - | expression tag |
| Leu 487 | - | expression tag |
| Val 488 | - | expression tag |
| Pro 489 | - | expression tag |
| Arg 490 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1258 | - | expression tag |
| Ser 1259 | - | expression tag |
| Ala 1260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 149810.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1365.1 | |
| All* | Total formula weight | 151175.1 |
