4YIH
Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5'(3')-deoxyribonucleotidase, cytosolic type | polymer | 195 | 22805.2 | 2 | UniProt (Q8TCD5) Pfam (PF06941) | Homo sapiens (Human) | Cytosolic 5',3'-pyrimidine nucleotidase,Deoxy-5'-nucleotidase 1,dNT-1 |
| 2 | C, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, H (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E, I (A, B) | 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione | non-polymer | 502.3 | 2 | Chemie (2O2) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45610.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1335.3 | |
| All* | Total formula weight | 46945.6 |
