4YGF
Crystal structure of the complex of Helicobacter pylori alpha-Carbonic Anhydrase with acetazolamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Alpha-carbonic anhydrase | polymer | 234 | 27001.6 | 8 | UniProt (K4NGD4) Pfam (PF00194) UniProt (by SIFTS) (A0A0M3KL20) | Helicobacter pylori | |
| 2 | AA, DA, HA, I, M... (F, G, H, A, B...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | BA, EA, IA, J, N... (F, G, H, A, B...) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 4 | CA, FA, JA, K, O... (F, G, H, A, B...) | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 8 | Chemie (AZM) | |||
| 5 | GA, KA, L, S, Z (G, H, A, C, E) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | LA, MA, NA, OA, PA... (A, B, C, D, E...) | water | water | 18.0 | 1019 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 20 - 247 (UniProt: K4NGD4)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Ile 15 | - | expression tag |
| Asp 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Phe 18 | - | expression tag |
| Thr 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 216012.8 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 3045.3 | |
| All* | Total formula weight | 219058.1 |
