4YFX

Escherichia coli RNA polymerase in complex with Myxopyronin B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H	DNA-directed RNA polymerase subunit alpha	polymer	329	36558.7	4	UniProt (A7ZSI4) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB	Escherichia coli O139:H28 (strain E24377A / ETEC)	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	C, I	DNA-directed RNA polymerase subunit beta	polymer	1342	150820.9	2	UniProt (A7ZUK1) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) In PDB	Escherichia coli O139:H28 (strain E24377A / ETEC)	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	D, J	DNA-directed RNA polymerase subunit beta'	polymer	1407	155366.8	2	UniProt (A7ZUK2) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Escherichia coli O139:H28 (strain E24377A / ETEC)	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4	E, K	DNA-directed RNA polymerase subunit omega	polymer	91	10249.5	2	UniProt (A7ZTK1) Pfam (PF01192) In PDB	Escherichia coli O139:H28 (strain E24377A / ETEC)	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5	F, L	RNA polymerase sigma factor RpoD	polymer	613	70352.2	2	UniProt (P00579) Pfam (PF03979) Pfam (PF00140) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) In PDB	Escherichia coli (strain K12)	Sigma-70
6	D, J	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	D, J	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8	D	Myxopyronin B	non-polymer		431.5	1	Chemie (4C4)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	919813.6
Non-Polymers*	Number of molecules	7
	Total formula weight	741.8
All*	Total formula weight	920555.4

*Water molecules are not included.