4YFK
Escherichia coli RNA polymerase in complex with squaramide compound 8.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H (A, B, G, H) | DNA-directed RNA polymerase subunit alpha | polymer | 329 | 36558.7 | 4 | UniProt (A7ZSI4) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) | Escherichia coli O139:H28 (strain E24377A / ETEC) | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C, I (C, I) | DNA-directed RNA polymerase subunit beta | polymer | 1342 | 150820.9 | 2 | UniProt (A7ZUK1) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) | Escherichia coli O139:H28 (strain E24377A / ETEC) | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D, J (D, J) | DNA-directed RNA polymerase subunit beta' | polymer | 1407 | 155366.8 | 2 | UniProt (A7ZUK2) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | Escherichia coli O139:H28 (strain E24377A / ETEC) | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E, K (E, K) | DNA-directed RNA polymerase subunit omega | polymer | 91 | 10249.5 | 2 | UniProt (A7ZTK1) Pfam (PF01192) | Escherichia coli O139:H28 (strain E24377A / ETEC) | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F, L (F, L) | RNA polymerase sigma factor RpoD | polymer | 613 | 70352.2 | 2 | UniProt (P00579) Pfam (PF03979) Pfam (PF00140) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) | Escherichia coli (strain K12) | Sigma-70 |
| 6 | M, N, R, S (C, D, I, J) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 7 | O, P, T, U (D, J) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 8 | Q, V (D, J) | 3,5-dimethyl-N-{2-[4-(4-methylbenzyl)piperidin-1-yl]-3,4-dioxocyclobut-1-en-1-yl}-1,2-oxazole-4-sulfonamide | non-polymer | 443.5 | 2 | Chemie (4C6) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 919813.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1245.9 | |
| All* | Total formula weight | 921059.5 |
