4YF4

Crystal structure of Rv1284 in the presence of polycarpine at mildly acidic pH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Beta-carbonic anhydrase 1	polymer	172	19255.9	4	UniProt (P9WPJ6) Pfam (PF00484)	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	Beta-CA 1,Carbonate dehydratase 1,mtCA 1
2	E, H, J, M (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	F, I, K, N (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	G, L (A, C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	321	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 163 (UniProt: P9WPJ6)

PDB	External Database	Details
Met -8	-	initiating methionine
Ala -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77023.5
Non-Polymers*	Number of molecules	10
	Total formula weight	429.8
All*	Total formula weight	77453.2

*Water molecules are not included.