4YDL
Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G, A | Envelope glycoprotein gp160,Envelope glycoprotein gp160 | polymer | 353 | 39211.4 | 2 | UniProt (Q0ED31) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | H, B | HEAVY CHAIN OF ANTIBODY C38-VRC18.02 | polymer | 226 | 24402.5 | 2 | Homo sapiens (Human) | ||
3 | L, C | LIGHT CHAIN OF ANTIBODY C38-VRC18.02 | polymer | 211 | 23291.0 | 2 | Homo sapiens (Human) | ||
4 | A, C, G, L | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 22 | Chemie (NAG) | |||
5 | A, G | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
6 | C, L | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
7 | water | water | 18.0 | 1402 | Chemie (HOH) |
Sequence modifications
G, A: 44 - 123 (UniProt: Q0ED31)
G, A: 199 - 301 (UniProt: Q0ED31)
G, A: 324 - 492 (UniProt: Q0ED31)
G, A: 199 - 301 (UniProt: Q0ED31)
PDB | External Database | Details |
---|---|---|
Gly 124 | - | linker |
Gly 198 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 318 | - | linker |
Gly 319 | - | linker |
Ser 320 | - | linker |
Gly 321 | - | linker |
Ser 322 | - | linker |
Gly 323 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 173809.9 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 5631.4 | |
All* | Total formula weight | 179441.3 |