4YDJ
Crystal structure of broadly and potently neutralizing antibody 44-VRC13.01 in complex with HIV-1 clade AE strain 93TH057 gp120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G, I | Envelope glycoprotein gp160,Envelope glycoprotein gp160 | polymer | 353 | 39211.4 | 2 | UniProt (Q0ED31) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
| 2 | H, A | HEAVY CHAIN OF ANTIBODY 44-VRC13.01 | polymer | 238 | 25535.0 | 2 | Homo sapiens (Human) | ||
| 3 | L, B | LIGHT CHAIN OF ANTIBODY 44-VRC13.01 | polymer | 206 | 22175.5 | 2 | Homo sapiens (Human) | ||
| 4 | I, A, G, B, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 22 | Chemie (NAG) | |||
| 5 | A, H, L | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 3 | Chemie (IPA) | |||
| 6 | A, B, H | (R,R)-2,3-BUTANEDIOL | non-polymer | 90.1 | 4 | Chemie (BU3) | |||
| 7 | L | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | A, B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 9 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 10 | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence modifications
G, I: 44 - 196 (UniProt: Q0ED31)
G, I: 199 - 317 (UniProt: Q0ED31)
G, I: 324 - 492 (UniProt: Q0ED31)
G, I: 199 - 317 (UniProt: Q0ED31)
| PDB | External Database | Details |
|---|---|---|
| Gly 197 | - | linker |
| Gly 198 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 318 | - | linker |
| Gly 319 | - | linker |
| Ser 320 | - | linker |
| Gly 321 | - | linker |
| Ser 322 | - | linker |
| Gly 323 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 173843.9 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 5784.1 | |
| All* | Total formula weight | 179628.0 |
