4YDG
Crystal structure of compound 10 in complex with HTLV-1 Protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HTLV-1 protease | polymer | 116 | 12566.6 | 2 | UniProt (P03362) Pfam (PF00077) | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | Pr160Gag-Pro-Pol |
| 2 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | E (B) | N,N'-(3S,4S)-PYRROLIDINE-3,4-DIYLBIS(4-AMINO-N-BENZYLBENZENESULFONAMIDE) | non-polymer | 591.7 | 1 | Chemie (G3G) |
Sequence modifications
A, B: 1 - 116 (UniProt: P03362)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 489 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 783.9 | |
| All* | Total formula weight | 25917.0 |
