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4YD2

Nicked complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed DNA/RNA polymerase mupolymer35439844.21UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)Pol Mu,Terminal transferase
2B
(T)
DNA (5'-D(*CP*GP*GP*CP*AP*AP*T)-3')polymer103054.01Homo sapiens
3C
(P)
DNA (5'-D(*CP*GP*TP*AP*T)-3')polymer51495.01Homo sapiens
4D
(D)
DNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81Homo sapiens
5E, H, I
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
6F, G, J
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
7K
(A)
PYROPHOSPHATEnon-polymer178.01Chemie (PPV)
8L, M, N, O
(A, T, P, D)
waterwater18.0142Chemie (HOH)
Sequence modifications
A: 134 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 129-expression tag
Ser 130-expression tag
Ala 131-expression tag
Ala 132-expression tag
Ala 133-expression tag
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
Gly 410-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight45585.0
Non-Polymers*Number of molecules7
Total formula weight353.3
All*Total formula weight45938.3
*Water molecules are not included.

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PDB entries from 2025-06-25

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