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4YC7

Crystal structure of human FMNL2 GBD-FH3 Domains bound to Cdc42-GppNHp

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Formin-like protein 2polymer38144081.21UniProt (Q96PY5)
Pfam (PF06371)
Pfam (PF06367)
Homo sapiens (Human)Formin homology 2 domain-containing protein 2, FMNL2
2B
(A)
Cell division control protein 42 homologpolymer18120028.01UniProt (P60953)
Pfam (PF00071)
Homo sapiens (Human)G25K GTP-binding protein, Cdc42
3C
(A)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E, F
(B, A)
waterwater18.063Chemie (HOH)
Sequence modifications
B: 1 - 379 (UniProt: Q96PY5)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
A: 0 - 178 (UniProt: P60953)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ala -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight64109.2
Non-Polymers*Number of molecules2
Total formula weight546.5
All*Total formula weight64655.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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