4Y94
Crystal structure of the PH-TH module of Bruton's tyrosine kinase bound to inositol hexakisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, C, A, D) | Non-specific protein-tyrosine kinase | polymer | 171 | 20161.2 | 4 | UniProt (Q3ZC95) Pfam (PF00169) Pfam (PF00779) | Bos taurus (Bovine) | |
| 2 | E, G, I, J, L... (B, C, A, D) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 6 | Chemie (IHP) | |||
| 3 | F, H, K, N (B, C, A, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | O, P, Q, R (B, C, A, D) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
B, C, A, D: 1 - 170 (UniProt: Q3ZC95)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 80644.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4221.8 | |
| All* | Total formula weight | 84866.6 |
