4Y92
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-tyrosine kinase | polymer | 61 | 6906.6 | 1 | UniProt (Q64817) Pfam (PF00018) | Avian sarcoma virus PR2257/16 | |
| 2 | B (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H (A) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 85 - 141 (UniProt: Q64817)
| PDB | External Database | Details |
|---|---|---|
| Gly 81 | - | expression tag |
| Ser 82 | - | expression tag |
| His 83 | - | expression tag |
| Met 84 | - | expression tag |
| Thr 97 | Glu 97 | engineered mutation |
| Arg 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6906.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 614.6 | |
| All* | Total formula weight | 7521.2 |
