4Y6Q
Human SIRT2 in complex with 2-O-myristoyl-ADP-ribose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | NAD-dependent protein deacetylase sirtuin-2 | polymer | 293 | 33201.2 | 4 | UniProt (Q8IXJ6) Pfam (PF02146) In PDB | Homo sapiens (Human) | Regulatory protein SIR2 homolog 2,SIR2-like protein 2 |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B, C, D | [(2S,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] tetradecanoate | non-polymer | 769.7 | 4 | Chemie (OMR) | |||
| 4 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 52 - 356 (UniProt: Q8IXJ6)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 292 | deletion |
| - | Ser 293 | deletion |
| - | Asp 294 | deletion |
| - | Pro 295 | deletion |
| - | Phe 296 | deletion |
| - | Leu 297 | deletion |
| - | Gly 298 | deletion |
| - | Met 299 | deletion |
| - | Ile 300 | deletion |
| - | Met 301 | deletion |
| - | Gly 302 | deletion |
| - | Leu 303 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 132804.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3340.3 | |
| All* | Total formula weight | 136145.2 |
