4Y49
Crystal structure of yeast N-terminal acetyltransferase (ppGpp) NatE in complex with a bisubstrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, G, M) | N-terminal acetyltransferase A complex subunit NAT1 | polymer | 854 | 99084.2 | 3 | UniProt (P12945) Pfam (PF12569) | Saccharomyces cerevisiae (Baker's yeast) | NatA complex subunit NAT1,Amino-terminal,alpha-amino,acetyltransferase 1 |
| 2 | B, F, J (B, H, N) | N-terminal acetyltransferase A complex catalytic subunit ARD1 | polymer | 238 | 27635.2 | 3 | UniProt (P07347) Pfam (PF00583) | Saccharomyces cerevisiae (Baker's yeast) | NatA complex subunit ARD1,Arrest-defective protein 1 |
| 3 | C, G, K (C, I, O) | N-terminal acetyltransferase A complex subunit NAT5 | polymer | 176 | 19753.7 | 3 | UniProt (Q08689) Pfam (PF00583) | Saccharomyces cerevisiae (Baker's yeast) | NatA complex subunit NAT5 |
| 4 | D, H, L (E, K, Q) | ALA-ALA-ALA-ALA-ALA-ALA | polymer | 8 | 1058.2 | 3 | Pfam (PF00976) UniProt (by SIFTS) (P01189) | Homo sapiens | |
| 5 | M, P, S (A, G, M) | GUANOSINE-5',3'-TETRAPHOSPHATE | non-polymer | 603.2 | 3 | Chemie (G4P) PubChem (136364674) PubChem (135398637) PubChem (135402035) PubChem (135797842) PubChem (136122641) PubChem (136203484) PubChem (173818810) | |||
| 6 | N, Q, T (B, H, N) | CARBOXYMETHYL COENZYME *A | non-polymer | 825.6 | 3 | Chemie (CMC) PubChem (4627206) PubChem (444878) PubChem (101921345) | |||
| 7 | O, R, U (C, I, O) | ACETYL COENZYME *A | non-polymer | 809.6 | 3 | Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977) |
Sequence modifications
A, G, M: 12 - 865 (UniProt: P12945)
| PDB | External Database | Details |
|---|---|---|
| Tyr 31 | Glu 20 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 442593.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 6714.9 | |
| All* | Total formula weight | 449308.7 |
