4Y49
Crystal structure of yeast N-terminal acetyltransferase (ppGpp) NatE in complex with a bisubstrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, G, M) | N-terminal acetyltransferase A complex subunit NAT1 | polymer | 854 | 99084.2 | 3 | UniProt (P12945) Pfam (PF12569) | Saccharomyces cerevisiae (Baker's yeast) | NatA complex subunit NAT1,Amino-terminal,alpha-amino,acetyltransferase 1 |
| 2 | B, F, J (B, H, N) | N-terminal acetyltransferase A complex catalytic subunit ARD1 | polymer | 238 | 27635.2 | 3 | UniProt (P07347) Pfam (PF00583) | Saccharomyces cerevisiae (Baker's yeast) | NatA complex subunit ARD1,Arrest-defective protein 1 |
| 3 | C, G, K (C, I, O) | N-terminal acetyltransferase A complex subunit NAT5 | polymer | 176 | 19753.7 | 3 | UniProt (Q08689) Pfam (PF00583) | Saccharomyces cerevisiae (Baker's yeast) | NatA complex subunit NAT5 |
| 4 | D, H, L (E, K, Q) | ALA-ALA-ALA-ALA-ALA-ALA | polymer | 8 | 1058.2 | 3 | Pfam (PF00976) UniProt (by SIFTS) (P01189) | Homo sapiens | |
| 5 | M, P, S (A, G, M) | GUANOSINE-5',3'-TETRAPHOSPHATE | non-polymer | 603.2 | 3 | Chemie (G4P) | |||
| 6 | N, Q, T (B, H, N) | CARBOXYMETHYL COENZYME *A | non-polymer | 825.6 | 3 | Chemie (CMC) | |||
| 7 | O, R, U (C, I, O) | ACETYL COENZYME *A | non-polymer | 809.6 | 3 | Chemie (ACO) |
Sequence modifications
A, G, M: 12 - 865 (UniProt: P12945)
| PDB | External Database | Details |
|---|---|---|
| Tyr 31 | Glu 20 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 442593.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 6714.9 | |
| All* | Total formula weight | 449308.7 |
