4Y32
Crystal structure of C-terminal modified Tau peptide-hybrid 109B with 14-3-3sigma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 2 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | C, D (C, D) | ARG-THR-PRO-SEP-LEU-PRO-CNC(C(C)O)C(=O)N1CCCC1CCOC | polymer | 7 | 851.9 | 2 | UniProt (by SIFTS) (P10636) | Homo sapiens | |
| 3 | E (C) | (2S)-2-(2-methoxyethyl)pyrrolidine | non-polymer | 129.2 | 1 | Chemie (49F) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 761 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54789.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 129.2 | |
| All* | Total formula weight | 54918.8 |
