4Y0F

Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TAR DNA-binding protein 43	polymer	103	12064.7	2	UniProt (Q13148) Pfam (PF00076)	Homo sapiens (Human)	TDP-43
2	C, D (C, D)	DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3')	polymer	10	3091.0	2		Homo sapiens
3	E, F, G, H (A, B, C, D)	water	water		18.0	37	Chemie (HOH)

Sequence modifications

A, B: 101 - 191 (UniProt: Q13148)

PDB	External Database	Details
Met 89	-	expression tag
Arg 90	-	expression tag
Gly 91	-	expression tag
Ser 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag
Gly 99	-	expression tag
Ser 100	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	30311.5
All*	Total formula weight	30311.5

*Water molecules are not included.