4XZ2
Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-dependent 6-phosphofructokinase, platelet type | polymer | 761 | 83161.0 | 4 | UniProt (Q01813) Pfam (PF00365) | Homo sapiens (Human) | PFK-P,6-phosphofructokinase type C,Phosphofructo-1-kinase isozyme C,PFK-C,Phosphohexokinase |
| 2 | E, J, K, M, Q... (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) PubChem (1061) | |||
| 3 | F, H, L, O (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) PubChem (16219368) PubChem (718) PubChem (24802138) PubChem (10267) PubChem (46937007) PubChem (172313) PubChem (440117) PubChem (89534552) PubChem (445557) PubChem (92209487) PubChem (92209485) PubChem (92209486) PubChem (124383956) PubChem (124540446) PubChem (5702629) PubChem (135053794) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (12800340) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795) | |||
| 4 | G, N (B, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 5 | I, P (B, D) | 6-O-phosphono-beta-D-fructofuranose | non-polymer | 260.1 | 2 | Chemie (F6P) |
Sequence modifications
A, B, C, D: 26 - 762 (UniProt: Q01813)
| PDB | External Database | Details |
|---|---|---|
| Met 2 | - | initiating methionine |
| Ala 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Trp 5 | - | expression tag |
| Ser 6 | - | expression tag |
| His 7 | - | expression tag |
| Pro 8 | - | expression tag |
| Gln 9 | - | expression tag |
| Phe 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Lys 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Asp 15 | - | expression tag |
| Asp 16 | - | expression tag |
| Asp 17 | - | expression tag |
| Asp 18 | - | expression tag |
| Lys 19 | - | expression tag |
| Val 20 | - | expression tag |
| Pro 21 | - | expression tag |
| Asp 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Thr 24 | - | expression tag |
| Ser 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 332644.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3305.0 | |
| All* | Total formula weight | 335949.1 |
