4XZ1
ZAP-70-tSH2:Compound-B adduct
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase ZAP-70 | polymer | 262 | 29515.8 | 1 | UniProt (P43403) Pfam (PF00017) | Homo sapiens (Human) | 70 kDa zeta-chain associated protein,Syk-related tyrosine kinase |
| 2 | B (B) | doubly phosphorylated ITAM peptide | polymer | 21 | 2675.7 | 1 | Pfam (PF02189) UniProt (by SIFTS) (P20963) | Homo sapiens | |
| 3 | C (A) | 2-[(7-chloro-4-nitro-2,1,3-benzoxadiazol-5-yl)amino]ethanol | non-polymer | 258.6 | 1 | Chemie (4N6) |
Sequence modifications
A: 1 - 259 (UniProt: P43403)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 117 | Cys 117 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32191.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 258.6 | |
| All* | Total formula weight | 32450.0 |
