4XY8
Crystal Structure of the bromodomain of BRD9 in complex with a 2-amine-9H-purine ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 9 | polymer | 123 | 14249.8 | 1 | UniProt (Q9H8M2) Pfam (PF00439) | Homo sapiens (Human) | Rhabdomyosarcoma antigen MU-RMS-40.8, BRD9 |
| 2 | B (A) | 6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine | non-polymer | 320.1 | 1 | Chemie (43U) | |||
| 3 | C (A) | BROMIDE ION | non-polymer | 79.9 | 1 | Chemie (BR) | |||
| 4 | D (A) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence modifications
A: 14 - 134 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | - | expression tag |
| Met 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14249.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 400.0 | |
| All* | Total formula weight | 14649.8 |
