4XY8
Crystal Structure of the bromodomain of BRD9 in complex with a 2-amine-9H-purine ligand
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 43U A 201 |
| Chain | Residue |
| A | PHE44 |
| A | HOH388 |
| A | PHE47 |
| A | VAL49 |
| A | ILE53 |
| A | TYR99 |
| A | ASN100 |
| A | TYR106 |
| A | HIS115 |
| A | HOH331 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 202 |
| Chain | Residue |
| A | VAL105 |
| A | LYS123 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding => ECO:0000269|PubMed:26365797 |
| Chain | Residue | Details |
| A | ILE53 | |
| A | TYR106 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q3UQU0 |
| Chain | Residue | Details |
| A | GLY56 |
