4XXV

Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3-isopropylmalate dehydrogenase	polymer	363	39315.8	2	UniProt (Q2T7H6) Pfam (PF00180) In PDB	Burkholderia thailandensis	3-IPM-DH,Beta-IPM dehydrogenase,IMDH
2	B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
3	B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	964	Chemie (HOH)

Sequence modifications

A, B: 1 - 355 (UniProt: Q2T7H6)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78631.6
Non-Polymers*	Number of molecules	3
	Total formula weight	847.6
All*	Total formula weight	79479.2

*Water molecules are not included.