4XXO

Crystal Structure of Human APOBEC3A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA dC->dU-editing enzyme APOBEC-3A	polymer	203	23300.3	2	UniProt (P31941) Pfam (PF05240)	Homo sapiens (Human)	A3A,Phorbolin-1
2	C, D, E, F, G... (A, B)	ZINC ION	non-polymer		65.4	7	Chemie (ZN)
3	H, K (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	L, M (A, B)	water	water		18.0	75	Chemie (HOH)

Sequence modifications

A, B: 1 - 199 (UniProt: P31941)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag
Ala 72	Glu 72	engineered mutation
Ala 171	Cys 171	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46600.6
Non-Polymers*	Number of molecules	9
	Total formula weight	528.8
All*	Total formula weight	47129.3

*Water molecules are not included.