4XWG
Crystal Structure of LCAT (C31Y) in complex with Fab1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Fab1 Light Chain | polymer | 213 | 22744.1 | 1 | Homo sapiens | ||
| 2 | B (H) | Fab1 Heavy Chain | polymer | 238 | 25644.6 | 1 | Homo sapiens | ||
| 3 | C (A) | Phosphatidylcholine-sterol acyltransferase | polymer | 422 | 47983.5 | 1 | UniProt (P04180) Pfam (PF02450) | Homo sapiens (Human) | Lecithin-cholesterol acyltransferase,Phospholipid-cholesterol acyltransferase |
| 4 | D, E, F, G, K... (L, A) | ZINC ION | non-polymer | 65.4 | 16 | Chemie (ZN) | |||
| 5 | H, I, J (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | W, X, Y (L, H, A) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A: 1 - 416 (UniProt: P04180)
| PDB | External Database | Details |
|---|---|---|
| Tyr 31 | Cys 55 | engineered mutation |
| Glu 417 | - | expression tag |
| Asn 418 | - | expression tag |
| Leu 419 | - | expression tag |
| Tyr 420 | - | expression tag |
| Phe 421 | - | expression tag |
| Gln 422 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96372.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1710.2 | |
| All* | Total formula weight | 98082.4 |
