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4XUM

PPARgamma ligand binding domain in complex with indomethacin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27831734.92UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2C, D, E
(A, B)
INDOMETHACINnon-polymer357.83Chemie (IMN)
3F, G
(A, B)
waterwater18.066Chemie (HOH)
Sequence modifications
A, B: 204 - 477 (UniProt: P37231)
PDBExternal DatabaseDetails
Gly 200-expression tag
Ser 201-expression tag
His 202-expression tag
Met 203-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63469.7
Non-Polymers*Number of molecules3
Total formula weight1073.4
All*Total formula weight64543.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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