4XUH
PPARgamma ligand binding domain in complex with sulindac sulfide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 278 | 31734.9 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | C, D, E, F (A, B) | 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfanylphenyl)methylidene]inden-1-yl]ethanoic acid | non-polymer | 340.4 | 4 | Chemie (SFI) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 204 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 200 | - | expression tag |
| Ser 201 | - | expression tag |
| His 202 | - | expression tag |
| Met 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63469.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1361.6 | |
| All* | Total formula weight | 64831.4 |
