4XT3

Structure of a viral GPCR bound to human chemokine CX3CL1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	G-protein coupled receptor homolog US28	polymer	362	42041.1	1	UniProt (P69332) Pfam (PF00001)	Cytomegalovirus	HHRF3
2	B (B)	Fractalkine	polymer	91	10013.5	1	UniProt (P78423) Pfam (PF00048)	Homo sapiens (Human)	C-X3-C motif chemokine 1,CX3C membrane-anchored chemokine,Neurotactin,Small-inducible cytokine D1
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		627.6	1	In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ)		triacetyl-beta-chitotriose
4	D (A)	UNKNOWN LIGAND	non-polymer		95.0	1	Chemie (UNL)
5	E (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)

Sequence modifications

A: 1 - 354 (UniProt: P69332)

PDB	External Database	Details
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Ala 0	-	expression tag

B: 1 - 77 (UniProt: P78423)

PDB	External Database	Details
Ser 78	-	expression tag
Gly 79	-	expression tag
Ser 80	-	expression tag
Gly 81	-	expression tag
Ser 82	-	expression tag
Ala 83	-	expression tag
Ala 84	-	expression tag
Ala 85	-	expression tag
Leu 86	-	expression tag
Glu 87	-	expression tag
Val 88	-	expression tag
Leu 89	-	expression tag
Phe 90	-	expression tag
Gln 91	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52054.6
Branched	Number of molecules	1
	Total formula weight	627.6
Non-Polymers*	Number of molecules	2
	Total formula weight	189.9
All*	Total formula weight	52872.1

*Water molecules are not included.