4XRM
homodimer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (M) | DNA (5'-D(P*AP*GP*CP*TP*GP*AP*CP*AP*GP*CP*TP*GP*TP*CP*AP*AP*G)-3') | polymer | 17 | 5236.4 | 1 | synthetic construct | ||
| 2 | B (L) | DNA (5'-D(P*TP*CP*TP*TP*GP*AP*CP*AP*GP*CP*TP*GP*TP*CP*AP*GP*C)-3') | polymer | 17 | 5178.4 | 1 | synthetic construct | ||
| 3 | C, D (A, B) | Homeobox protein Meis2 | polymer | 64 | 7517.7 | 2 | UniProt (O14770) Pfam (PF05920) | Homo sapiens (Human) | Meis1-related protein 1 |
| 4 | E, F (M, L) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 5 | G, H, I, J (M, L, A, B) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence modifications
A, B: 277 - 338 (UniProt: O14770)
| PDB | External Database | Details |
|---|---|---|
| Ser 275 | - | expression tag |
| Met 276 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 25450.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 244.3 | |
| All* | Total formula weight | 25694.4 |
