4XRM

homodimer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue TRS M 101

Chain	Residue
A	ASN320
M	HOH224
A	ILE324
A	HOH409
L	HOH230
M	DG9
M	DC10
M	HOH204
M	HOH214
M	HOH217

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site_id	AC2
Number of Residues	10
Details	binding site for residue TRS L 101

Chain	Residue
B	ASN320
B	ILE324
B	HOH410
L	DG29
L	DC30
L	HOH209
L	HOH212
L	HOH217
L	HOH225
L	HOH230

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	Region: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"26550823","evidenceCode":"ECO:0000305"},{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"OCT-2015","submissionDatabase":"PDB data bank","title":"Molecular basis of recognition of two distinct DNA sequences by a single transcription factor.","authors":["Morgunova E.","Yin Y.","Jolma A.","Popov A.","Taipale J."]}}]}

Chain

Residue

Details

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