4XQU

Crystal structure of hemagglutinin from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 3'-SLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin HA1	polymer	326	35682.3	3	UniProt (A0A059T4A1) Pfam (PF00509)	Influenza A virus
2	B, D, F (B, D, F)	Hemagglutinin HA2	polymer	181	20755.8	3	UniProt (A0A059T4A1) Pfam (PF00509)	Influenza A virus
3	G, I (G, I)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	2	In PDB BIRD (PRD_900067) GlyTouCan (G00065MO)		3'-sialyl-N-acetyllactosamine
4	H, J (H, J)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	K (K)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose	branched		471.4	1	In PDB GlyTouCan (G30207PZ)
6	L, M, N (A, C, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, C, E: 11 - 330 (UniProt: A0A059T4A1)

PDB	External Database	Details
Ala 8	-	expression tag
Asp 9	-	expression tag
Pro 10	-	expression tag

B, D, F: 1 - 174 (UniProt: A0A059T4A1)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag
Leu 178	-	expression tag
Val 179	-	expression tag
Pro 180	-	expression tag
Arg 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	169314.2
Branched	Number of molecules	5
	Total formula weight	2669.4
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	172647.3

*Water molecules are not included.