4XQ6

CRYSTAL STRUCTURE OF DIHYDROOROTATE DEHYDROGENSE from MYCOBACTERIUM TUBERCULOSIS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydroorotate dehydrogenase (quinone)	polymer	344	36465.4	2	UniProt (A5U4G5) Pfam (PF01180) UniProt (by SIFTS) (P9WHL1)	Mycobacterium tuberculosis H37Ra	DHOdehase, DHODase, Dihydroorotate oxidase
2	C, G (A, B)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
3	D, E, H, I, J (A, B)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
4	F (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	K, L (A, B)	water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 31 - 353 (UniProt: A5U4G5)

PDB	External Database	Details
Met 10	-	expression tag
Gly 11	-	expression tag
Ser 12	-	expression tag
Ser 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
Ser 20	-	expression tag
Ser 21	-	expression tag
Gly 22	-	expression tag
Leu 23	-	expression tag
Val 24	-	expression tag
Pro 25	-	expression tag
Arg 26	-	expression tag
Gly 27	-	expression tag
Ser 28	-	expression tag
His 29	-	expression tag
Met 30	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72930.8
Non-Polymers*	Number of molecules	8
	Total formula weight	1114.3
All*	Total formula weight	74045.1

*Water molecules are not included.