4XP3
Crystal structure of ERK2 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 351 | 40925.1 | 1 | UniProt (P63086) Pfam (PF00069) | Rattus norvegicus (Rat) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
| 2 | B (A) | 2-amino-1,9-dihydro-6H-purine-6-thione | non-polymer | 167.2 | 1 | Chemie (DX4) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E, F, G, H... (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 11 | Chemie (DMS) | |||
| 5 | O (A) | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40925.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1122.7 | |
| All* | Total formula weight | 42047.8 |
