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4XOY

Crystal structure of ERK2 in complex with an inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 1polymer35141077.41UniProt (P63086)
Pfam (PF00069)
Rattus norvegicus (Norway Rat)MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2
2B
(A)
2-amino-1,9-dihydro-6H-purine-6-thionenon-polymer167.21Chemie (DX4)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.0143Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41077.4
Non-Polymers*Number of molecules2
Total formula weight263.3
All*Total formula weight41340.6
*Water molecules are not included.

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PDB entries from 2025-02-05

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