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4XN5

Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Phenylalanine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Aminopeptidase Npolymer86698480.01UniProt (P04825)
Pfam (PF17900)
Pfam (PF01433)
Pfam (PF11940)
Pfam (PF17432)
Escherichia coli (strain K12)Alpha-aminoacylpeptide hydrolase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
PHENYLALANINEnon-polymer165.21Chemie (PHE)
4D, E, F
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
5G, H, I, J
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
6K, L, M, N, O...
(A)
MALONATE IONnon-polymer102.07Chemie (MLI)
7R
(A)
waterwater18.0519Chemie (HOH)
Sequence modifications
A: 5 - 870 (UniProt: P04825)
PDBExternal DatabaseDetails
Ala 260Met 260engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight98480.0
Non-Polymers*Number of molecules16
Total formula weight1382.3
All*Total formula weight99862.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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