4XMX
Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with Bestatin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aminopeptidase N | polymer | 866 | 98480.0 | 1 | UniProt (P04825) Pfam (PF17900) Pfam (PF01433) Pfam (PF11940) Pfam (PF17432) | Escherichia coli (strain K12) | Alpha-aminoacylpeptide hydrolase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID | non-polymer | 308.4 | 1 | Chemie (BES) | |||
| 4 | D, E, F, G, H (A) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 5 | I, J, K, L, M... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | AA, O, P, Q, R... (A) | MALONATE ION | non-polymer | 102.0 | 13 | Chemie (MLI) | |||
| 7 | BA (A) | water | water | 18.0 | 656 | Chemie (HOH) |
Sequence modifications
A: 5 - 870 (UniProt: P04825)
| PDB | External Database | Details |
|---|---|---|
| Ala 260 | Met 260 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 98480.0 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2367.9 | |
| All* | Total formula weight | 100847.9 |
