4XHJ
gHgL of Varicella-zoster virus in complex with human neutralizing antibodies.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Envelope glycoprotein H | polymer | 833 | 92763.6 | 2 | UniProt (Q775J3) Pfam (PF02489) Pfam (PF17488) | Human herpesvirus 3 strain Oka vaccine (HHV-3) | gH,Glycoprotein III,GPIII |
| 2 | B, F (B, F) | Envelope glycoprotein L | polymer | 138 | 15197.2 | 2 | UniProt (Q9J3N1) Pfam (PF05259) | Human herpesvirus 3 strain Oka vaccine (HHV-3) | gL |
| 3 | C, G (C, G) | Fab-RC light chain | polymer | 215 | 23549.3 | 2 | Homo sapiens | ||
| 4 | D, H (D, H) | Fab-RC heavy chain | polymer | 282 | 30338.1 | 2 | Homo sapiens | ||
| 5 | I (I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | J, M (J, M) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 7 | K, L (K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | N, O, P (A, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, E: 1 - 795 (UniProt: Q775J3)
| PDB | External Database | Details |
|---|---|---|
| Gly 796 | - | expression tag |
| Ser 797 | - | expression tag |
| Glu 798 | - | expression tag |
| Asn 799 | - | expression tag |
| Leu 800 | - | expression tag |
| Tyr 801 | - | expression tag |
| Phe 802 | - | expression tag |
| Gln 803 | - | expression tag |
| Gly 804 | - | expression tag |
| Ser 805 | - | expression tag |
| Trp 806 | - | expression tag |
| Ser 807 | - | expression tag |
| His 808 | - | expression tag |
| Pro 809 | - | expression tag |
| Gln 810 | - | expression tag |
| Phe 811 | - | expression tag |
| Glu 812 | - | expression tag |
| Lys 813 | - | expression tag |
| Gly 814 | - | expression tag |
| Gly 815 | - | expression tag |
| Gly 816 | - | expression tag |
| Ser 817 | - | expression tag |
| Gly 818 | - | expression tag |
| Gly 819 | - | expression tag |
| Gly 820 | - | expression tag |
| Ser 821 | - | expression tag |
| Gly 822 | - | expression tag |
| Gly 823 | - | expression tag |
| Gly 824 | - | expression tag |
| Ser 825 | - | expression tag |
| Trp 826 | - | expression tag |
| Ser 827 | - | expression tag |
| His 828 | - | expression tag |
| Pro 829 | - | expression tag |
| Gln 830 | - | expression tag |
| Phe 831 | - | expression tag |
| Glu 832 | - | expression tag |
| Lys 833 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 323696.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3257.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 327616.9 |
