4XH9
CRYSTAL STRUCTURE OF HUMAN RHOA IN COMPLEX WITH DH/PH FRAGMENT OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR NET1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Neuroepithelial cell-transforming gene 1 protein | polymer | 361 | 42232.4 | 2 | UniProt (Q7Z628) Pfam (PF00621) Pfam (PF00169) In PDB | Homo sapiens (Human) | Proto-oncogene p65 Net1,Rho guanine nucleotide exchange factor 8 |
2 | B, E | Transforming protein RhoA | polymer | 180 | 20289.2 | 2 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
3 | water | water | 18.0 | 921 | Chemie (HOH) |
Sequence modifications
A, D: 149 - 501 (UniProt: Q7Z628)
B, E: 2 - 180 (UniProt: P61586)
PDB | External Database | Details |
---|---|---|
Met 147 | - | initiating methionine |
Gly 148 | - | expression tag |
His 502 | - | expression tag |
His 503 | - | expression tag |
His 504 | - | expression tag |
His 505 | - | expression tag |
His 506 | - | expression tag |
His 507 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 125043.1 | |
All* | Total formula weight | 125043.1 |