4XES
Structure of active-like neurotensin receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Neurotensin receptor type 1, Endolysin chimera | polymer | 541 | 60685.8 | 1 | UniProt (P20789) UniProt (P00720) Pfam (PF00001) Pfam (PF00959) In PDB | Rattus norvegicus (Rat) | NTR1, High-affinity levocabastine-insensitive neurotensin receptor, NTRH,Lysis protein, Lysozyme, Muramidase |
2 | B | Neurotensin/neuromedin N | polymer | 6 | 819.0 | 1 | UniProt (P20068) In PDB | Rattus norvegicus | |
3 | A | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
6 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
7 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 43 - 988 (UniProt: P20789)
A: 1002 - 1161 (UniProt: P00720)
PDB | External Database | Details |
---|---|---|
Asp 33 | - | expression tag |
Tyr 34 | - | expression tag |
Lys 35 | - | expression tag |
Asp 36 | - | expression tag |
Asp 37 | - | expression tag |
Asp 38 | - | expression tag |
Asp 39 | - | expression tag |
Ala 40 | - | expression tag |
Thr 41 | - | expression tag |
Ser 42 | - | expression tag |
Leu 86 | Ala 86 | engineered mutation |
Ala 166 | Glu 166 | engineered mutation |
Ala 215 | Gly 215 | engineered mutation |
Ala 360 | Val 360 | engineered mutation |
Ala 989 | - | linker |
His 990 | - | linker |
His 991 | - | linker |
His 992 | - | linker |
His 993 | - | linker |
His 994 | - | linker |
His 995 | - | linker |
His 996 | - | linker |
His 997 | - | linker |
His 998 | - | linker |
His 999 | - | linker |
Gly 1000 | - | linker |
Gly 1001 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 1012 | Arg 12 | conflict |
Thr 1054 | Cys 54 | conflict |
Ala 1097 | Cys 97 | conflict |
Asn 1122 | Gln 122 | conflict |
Asn 1123 | Gln 123 | conflict |
Arg 1137 | Ile 137 | conflict |
Gly 1162 | - | expression tag |
Ser 1163 | - | expression tag |
Gly 1164 | - | expression tag |
Ser 1165 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 61504.8 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 1475.6 | |
All* | Total formula weight | 62980.4 |