4XE0
Idelalisib bound to the p110 subunit of PI3K delta
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 939 | 107766.6 | 1 | UniProt (O35904) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Mus musculus (Mouse) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | B (A) | 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4(3H)-one | non-polymer | 415.4 | 1 | Chemie (40L) | |||
| 3 | C (A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A: 106 - 1044 (UniProt: O35904)
| PDB | External Database | Details |
|---|---|---|
| Gln 508 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 107766.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 415.4 | |
| All* | Total formula weight | 108182.0 |
