4XDE
Coagulation Factor XII protease domain crystal structure
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Coagulation factor XII | polymer | 257 | 27877.2 | 1 | UniProt (P00748) Pfam (PF00089) In PDB | Homo sapiens (Human) | Hageman factor,HAF |
2 | A | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
3 | A | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
4 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 354 - 596 (UniProt: P00748)
PDB | External Database | Details |
---|---|---|
Arg 352 | - | expression tag |
Ser 353 | - | expression tag |
Ser 467 | Cys 486 | engineered mutation |
His 597 | - | expression tag |
His 598 | - | expression tag |
Thr 599 | - | expression tag |
Gly 600 | - | expression tag |
Thr 601 | - | expression tag |
Arg 602 | - | expression tag |
His 603 | - | expression tag |
His 604 | - | expression tag |
His 605 | - | expression tag |
His 606 | - | expression tag |
His 607 | - | expression tag |
His 608 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 27877.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 309.3 | |
All* | Total formula weight | 28186.5 |