4XCS

Human peroxiredoxin-1 C83S mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Peroxiredoxin-1	polymer	219	24294.7	6	UniProt (Q06830) Pfam (PF00578) Pfam (PF10417)	Homo sapiens (Human)	Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2
2	G, I, L (A, C, F)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
3	H, J, K (A, D, E)	3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE	non-polymer		614.9	3	Chemie (CPS)
4	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	399	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 199 (UniProt: Q06830)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ser 83	Cys 83	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	145767.9
Non-Polymers*	Number of molecules	6
	Total formula weight	2120.9
All*	Total formula weight	147888.8

*Water molecules are not included.