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4XBE

Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: crystals cryoprotected with sphingomyelin (02:0 SM (d18:1/2:0)).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
4E10 FAB LIGHT CHAINpolymer21523395.81Homo sapiens
2B
(H)
4E10 Fab heavy chainpolymer23024180.31Homo sapiens
3C
(P)
PEPTIDE FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the region 671-683 of the MPERpolymer152058.41UniProt (by SIFTS) (P05877)Human immunodeficiency virus 1
4D, E
(L, H)
UNKNOWN LIGANDnon-polymer2Chemie (UNL)
5F, G, H
(L, H, P)
waterwater18.0463Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight49634.5
Non-Polymers*Number of molecules2
Total formula weight0.0
All*Total formula weight49634.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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